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SON Formula Tablets (International Nutrition Research)
- Drugs index
SON Formula® (MAP®) is a patented (U.S. Patent No. 5,132,113) dietary protein substitute that provides a unique pattern of essential amino acids, in a highly purified, free, crystalline form. After oral ingestion, SON Formula® is rapidly utilized. SON Formula® does not require the aid of peptidases and therefore is absorbed within 23 minutes, through the first 100 cm of functional small intestine. SON Formula® does not provide any fecal residue. SON Formula® is amphoteric. SON Formula® is supplied in tablets of 1,000 mg for oral administration. Each tablet of SON Formula® contains only the active ingredient MAP®. SON Formula® contains no inactive ingredients.
SON Formula®, in a dose of 10 g (10 tablets), provides the following essential amino acids profile:
The results of comparative, double-blind, triple and quintuple crossover Net Nitrogen Utilization (NNU) clinical studies have shown that the subjects, while taking MAP®, as a dietary protein substitute, achieved a body's 99% NNU. This means that 99% of MAP's constituent amino acids followed the anabolic pathway, thus acting as precursor of body's protein synthesis. By comparison, the most nutritious dietary proteins only provide an average of 32% NNU. Hence, MAP is more nutritious than dietary proteins. This has been confirmed by the fact that during the studies, each subject body's nitrogen balance was maintained in equilibrium by taking MAP, as a sole and total substitute of dietary proteins, in a dosage of only 400 mg/kg/day, which provided less than 2 kcal/day (1g MAP = 0.04 Kcal). The studies results have also shown that 1% of MAP's constituent amino acids followed the catabolic pathway, thus releasing only 1% of nitrogen catabolites and energy. By comparison dietary proteins release an average of 68% nitrogen catabolites and energy. These facts evidence that MAP is safer than dietary proteins, and provides the lowest amount of energy in comparison to any dietary protein.
To illustrate: when a dietary protein is digested, it releases its constituent amino acids into the small intestine where they are absorbed. Then, those amino acids can follow either the anabolic pathway or the catabolic pathway (Fig. I).
When dietary amino acids follow the anabolic pathway , they act as precursors for the body's protein synthesis, thus becoming the body's constituent proteins. Throughout the anabolic pathway amino acids do not release any nitrogen catabolites or energy (Fig. II).
On the other hand, when dietary amino acids follow the catabolic pathway , they act only as a source of energy and not as precursors of body's proteins synthesis. Throughout the catabolic pathway , amino acids do release nitrogen catabolites and energy (Fig. III).
INDICATIONS AND USAGE
SON Formula® is indicated as a safe and effective substitute for dietary proteins.
No adverse reactions have been reported.
No adverse reactions have been reported.
DOSAGE AND ADMINISTRATION
SON Formula® should be administered with food. SON Formula® in a dosage of 400mg/kg/day has been shown to be adequate, as a sole and total substitute of dietary proteins, to maintain the body's nitrogen balance in equilibrium. To calculate the SON Formula® dosage necessary to substitute dietary proteins, apply the following:
SON Formula® dosage = (Dietary Protein × 0.4) g
For instance: to calculate the dosage of SON Formula® necessary to substitute 10 g of dietary proteins, proceed as follows:
Therefore, 4 g (4 tablets) of SON Formula® provide a body's protein synthesis equivalent to that provided by at least 10 g of the most nutritious dietary protein.
SON Formula® is available in bottles of 100 tablets of 1,000 mg, for oral administration.
Additional professional information on SON Formula® is available thorough the International Nutritional Research Center, Inc.
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