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Medical Dictionary


dermophlebitis (der′mo-fle-bi′tis)
Inflammation of the superficial veins and the surrounding skin. [dermo- + G. phleps, vein, + -itis, inflammation]

dermoskeleton (der-mo-skel′e-ton)
SYN: exoskeleton (1) .

dermostenosis (der′mo-ste-no′sis)
Pathologic contraction of the skin. [dermo- + G. stenosis, a narrowing]

dermotoxin (der-mo-tok′sin)
A substance elaborated by a living agent, especially an exotoxin formed by bacteria, and characterized by its ability to cause pathologic changes in skin, e.g., erythema, degenerative changes, necrosis.

dermotropic (der-mo-trop′ik)
SYN: dermatotropic.

dermovascular (der-mo-vas′ku-lar)
Pertaining to the blood vessels of the skin. [dermo- + L. vasculum, small vessel]

derodidymus (dar′o-did′i-mus)
SYN: dicephalus diauchenos. [G. dere, neck, + didymos, twin]

derotation (de-ro-ta′shun)
1. A turning back. 2. In orthopedics, the correction of a rotation deformity by turning or rotating the deformed structure toward a normal position. [L. de, away, + rotatio, turning]

Abbreviation for diethylstilbestrol.

In chemistry, a prefix indicating absence of some component of the principal part of the name; largely replaced by “de-” ( e.g., deoxyribonucleic acid, dehydro-) but retained where “de-” could be taken for d- or d-, as part of “desmo-” ( e.g., desmosterol), and in such terms as desoxycortone.

desamidize (de-sam′i-diz)
SYN: deamidize.

De Sanctis
Carlo, Italian psychiatrist, *1888. See D.-Cacchione syndrome.

desaturate (de-sat′u-rat)
To produce desaturation.

desaturation (de′sat-u-ra′shun)
1. The act, or the result of the act, of making something less completely saturated; more specifically, the percentage of total binding sites remaining unfilled, e.g., when hemoglobin is 70% saturated with oxygen and nothing else, its d. is 30%. Cf.:saturation (5) . 2. The process or reaction of removal of two hydrogen atoms from a molecule, resulting in the formation of a double bond.

Pierre-Joseph, French surgeon, 1744–1795. See D. bandage.

Descartes, Cartesius
René, French philosopher, mathematician, physiologist, 1596–1650. The founder of modern philosophy and proponent of the mechanistic school or iatromathematical school. See D. law.

Jean, French physician, 1732–1810. See D. membrane.

descemetitis (des′e-me-ti′tis)
Inflammation of Descemet membrane.

descemetocele (des-e-met′o-sel)
A bulging forward of Descemet membrane caused by the destruction of the substance of the cornea by infection.

descendens (de-sen′denz)
SYN: descending. [L.] d. cervicalis SYN: inferior root of ansa cervicalis. d. hypoglossi SYN: superior root of ansa cervicalis.

descending (de-send′ing)
Running downward or toward the periphery. SYN: descendens. [L. de-scendo, pp. -scensus, to come down, fr. scando, to climb]

descensus (de-sen′sus)
A falling away from a higher position. SEE ALSO: ptosis, procidentia. SYN: descent (1) . [L.] d. testis descent of the testis from the abdomen into the scrotum during the seventh and eighth months of intrauterine life. d. uteri SYN: prolapse of the uterus. d. ventriculi SYN: gastroptosis.

descent (de-sent′)
1. SYN: descensus. 2. In obstetrics, the passage of the presenting part of the fetus into and through the birth canal. [L. descensus]

Joseph F.L., French surgeon, 1740–1824. See D. needle.

desensitization (de-sen′si-ti-za′shun)
1. The reduction or abolition of allergic sensitivity or reactions to the specific antigen (allergen). SYN: antianaphylaxis. 2. The act of removing an emotional complex. SYN: hyposensitization. heterologous d. stimulation by one agonist which leads to a broad pattern of unresponsiveness to further stimulation by a variety of other agonists. homologous d. loss of sensitivity only to the class of agonist used to desensitize the tissue. systematic d. a type of behavior therapy for eliminating phobias or anxieties: the patient and therapist construct a list of imagined scenes eliciting the phobia, ranked from least to most anxiety producing; the patient then is trained in deep muscle relaxation, and is repeatedly asked to imagine him or herself in the presence of the least anxiety-producing scene on the list until the patient feels fully relaxed while doing so; the procedure is repeated for each scene on the list until the patient develops the capacity to feel relaxed with any of the anxiety-producing scenes; real life scenes are then substituted for the imagined scenes. SYN: reciprocal inhibition (2) .

desensitize (de-sen′si-tiz)
1. To reduce or remove any form of sensitivity. 2. To effect desensitization (1). 3. In dentistry, to eliminate or subdue the painful response of exposed, vital dentin to irritative agents or thermal changes.

deserpidine (de-ser′pi-den)
Ester alkaloid isolated from Rauwolfia canescens (family Apocynaceae) with the same actions and uses as reserpine.

desetope (de′se-top)
That part of the Class II major histocompatibility molecule that interacts with the antigen. The term d. is derived from determinant selection. [determinant selection + -tope]

desferrioxamine mesylate (des′far-e-ok′sa-men)
SYN: deferoxamine mesylate.

desflurane (dés′floor′an)
An inhalation anesthetic with physical characteristics that provide rapid induction of and recovery from anesthesia.

deshydremia (des′hi-dre′me-a)
Hemoconcentration due to the loss of water from blood plasma. [L. de-, away from, + G. hydor, water, + haima, blood + -ia]

desiccant (des′i-kant)
1. Drying; causing or promoting dryness. SYN: desiccative. 2. An agent that absorbs moisture; a drying agent. SYN: desiccator (1) . SYN: exsiccant. [L. de-sicco, pp. -siccatus, to dry up]

desiccate (des′i-kat)
To dry thoroughly; to render free from moisture. SYN: exsiccate.

desiccation (des-i-ka′shun)
The process of being desiccated. SYN: dehydration (4) , exsiccation (1) .

desiccative (des-i-ka′tiv)
SYN: desiccant (1) .

desiccator (des′i-ka-ter, tor)
1. SYN: desiccant (2) . 2. An apparatus, such as a glass chamber containing calcium chloride, sulfuric acid, or other drying agent, in which a material is placed for drying. vacuum d. a d. that can be evacuated.

desipramine hydrochloride (des-ip′ra-men)
A dibenzazepine derivative; an antidepressant similar to imipramine hydrochloride. Selectively blocks reuptake of norepinephrine back into central aminergic neurons.

deslanoside (des-lan′o-sid)
A rapidly acting steroid glycoside obtained from lanatoside C (Digitalis lanata) by alkaline hydrolysis; a cardiotonic.

See desmo-.

Louis A., French ophthalmologist, 1810–1882. See D. dacryoliths, under dacryolith, D. retractor.

desmin (dez′minz)
Proteins found in intermediate filaments that copolymerizes with vimentin to form constituents of connective tissue, cell walls, filaments, etc. Found in Z disk of skeletal and cardiac muscle cells.

desmitis (dez-mi′tis)
Inflammation of a ligament. [desm- + G. -itis, inflammation]

desmo-, desm-
Fibrous connection; ligament. [G. desmos, a band]

desmocranium (dez-mo-kra′ne-um) [TA]
The mesenchymal primordium of the cranium.

desmodentium [TA]
The collagen fibers, running from the cementum to the alveolar bone, that suspend a tooth in its socket; they include apical, oblique, horizontal, and alveolar crest fibers, indicating that the orientation of the fibers varies at different levels. SYN: desmodontium [TA] , periodontal fiber&star, periodontal ligament fibers.

desmodontium [TA]
SYN: desmodentium.

Desmodus (dez′mo-dus)
A blood-feeding genus of Chiroptera, known generally as vampire bats, found in Trinidad, Mexico, and Central and South America; D. artibaeus, D. rotundus, and D. rufus, three species present in Trinidad and South America, are reservoir hosts of rabies virus. [desmo- + G. odous, tooth]

desmogenous (dez-moj′e-nus)
Of connective tissue or ligamentous origin or causation; e.g., denoting a deformity due to contraction of ligaments, fascia, or a scar. [desmo- + G. -gen, producing]

desmography (dez-mog′ra-fe)
A description of, or treatise on, the ligaments. [desmo- + G. grapho, to describe]

desmoid (dez′moyd)
1. Fibrous or ligamentous. 2. A nodule or relatively large mass of unusually firm scarlike connective tissue resulting from active proliferation of fibroblasts, occurring most frequently in the abdominal muscles of women who have borne children; the fibroblasts infiltrate surrounding muscle and fascia. SYN: abdominal fibromatosis, d. tumor. [desmo- + G. eidos, appearance, form] extra-abdominal d. a deep-seated firm tumor, most frequently occurring on the shoulders, chest, or back of young men or women, consisting of collagenous fibrous tissue that infiltrates surrounding muscle; frequently recurs but does not metastasize.

desmolases (dez′mo-la′sez)
Old and nonspecific term for enzymes catalyzing reactions other than those involving hydrolysis; e.g., those involving oxidation and reduction, isomerization, the breaking of carbon-carbon bonds.

desmology (dez-mol′o-je)
The branch of anatomy concerned with the ligaments. [desmo- + G. logos, study]

desmopathy (dez-mop′a-the)
Any disease of the ligaments. [desmo- + G. pathos, suffering]

desmoplasia (dez-mo-pla′ze-a)
Hyperplasia of fibroblasts and disproportionate formation of fibrous connective tissue, especially in the stroma of a carcinoma. [desmo- + G. plasis, a molding]

desmoplastic (des-mo-plas′tik)
1. Causing or forming adhesions. 2. Causing fibrosis in the vascular stroma of a neoplasm.

desmopressin (des-mo-pres′in)
An analog of vasopressin (antidiuretic hormone, ADH) possessing powerful antidiuretic activity. d. acetate a synthetic analog of vasopressin and an antidiuretic hormone.

desmosine (dez′mo-sen)
A cross-linking amino acid formed from lysyl residues found in elastin. [G. desmos, bond, fr. deo, to bind, + -ine]

desmosome (dez′mo-som)
A site of adhesion between two epithelial cells, consisting of a dense attachment plaque separated from a similar structure in the other cell by a thin layer of extracellular material. SYN: bridge corpuscle, macula adherens. [desmo- + G. soma, body]

desmosterol (dez-mos′ter-ol)
5α-Cholesta-5,24-diene-3β-ol;postulated intermediate in cholesterol biosynthesis from lanosterol via zymosterol; accumulates after prolonged administration of substances interfering with cholesterol biosynthesis. SYN: 24-dehydrocholesterol.

desonide (des′o-nid)
An anti-inflammatory corticosteroid used in topical preparations.

desoximetasone (des-ok-si-met′a-son)
An anti-inflammatory corticosteroid used in topical preparations.

See deoxy-.

desoxycorticosterone (des-oks-e-kor′ti-kos-ter-on)
A steroid derived from the adrenal cortex with strong mineralocorticoid activity.

desoxycortone (des-oks-e-kor′ton)
SYN: deoxycorticosterone.

despeciation (de-spe′she-a′shun)
1. Alteration of, or loss of species characteristics. 2. Removal of species-specific antigenic properties from a foreign protein.

Jean H.A., French physician, 1846–1930. See D. sign.

despumation (des-pu-ma′shun)
1. The rising of impurities to the surface of a liquid. 2. The skimming off of impurities on the surface of a liquid. [L. de-spumo, pp. -atus, to skim, fr. spumo, to foam, fr. spuma, foam]

desquamate (des′kwa-mat)
To shred, peel, or scale off, as the casting off of the epidermis in scales or shreds, or the shedding of the outer layer of any surface. [L. desquamo, pp. -atus, to scale off, fr. squama, a scale]

desquamation (des-kwa-ma′shun)
The shedding of the cuticle in scales or of the outer layer of any surface. branny d. SYN: defurfuration.

desquamative (des-kwam′a-tiv)
Relating to or marked by desquamation.

desthiobiotin (des′thi-o-bi′o-tin)
A compound derived from biotin by the removal of the sulfur atom; a precursor of biotin in bacteria and molds; it can substitute for biotin in some microorganisms, but is without effect on or is inhibitory to the growth of others.


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