1.	Content:

This chapter contains the following broad groups:
140-195	Malignant neoplasms, stated or presumed to be primary, of specified sites, except of
lymphatic and hematopoietic tissue
196-198	Malignant neoplasms, stated or presumed to be secondary, of specified sites
199	Malignant neoplasms, without specification of site
200-208	Malignant neoplasms, stated or presumed to be primary, of lymphatic and
 hematopoietic tissue
210-229	Benign neoplasms
230-234	Carcinoma in situ
235-238	Neoplasms of uncertain behavior [see Note, at beginning of section 235-238]
239	Neoplasms of unspecified nature

2.	Functional activity

All neoplasms are classified in this chapter, whether or not functionally active. An additional
code from Chapter 3 may be used to identify such functional activity associated with any
neoplasm, e.g.:
catecholamine-producing malignant pheochromocytoma of adrenal:
	code 194.0, additional code 255.6
basophil adenoma of pituitary with Cushing's syndrome:
	code 227.3, additional code 255.0

3.	Morphology [Histology]

For those wishing to identify the histological type of neoplasms, a comprehensive coded
nomenclature, which comprises the morphology rubrics of the ICD-Oncology, is given after the
 E-code chapter.

4.	Malignant neoplasms overlapping site boundaries

Categories 140-195 are for the classification of primary malignant neoplasms according to their
 point of origin.  A malignant neoplasm that overlaps two or more subcategories within a
 three-digit rubric and whose point of origin cannot be determined should be classified to the
 subcategory .8 "Other."  For example, "carcinoma involving tip and ventral surface of tongue"
 should be assigned to 141.8. On the other hand, "carcinoma of tip of tongue, extending to
 involve the ventral surface" should be coded to 141.2, as the point of origin, the tip, is
 known.  Three subcategories (149.8, 159.8, 165.8) have been provided for malignant neoplasms
 that overlap the boundaries of three-digit rubrics within certain systems.  Overlapping
 malignant neoplasms that cannot be classified as indicated above should be assigned to the
 appropriate subdivision of category 195 (Malignant neoplasm of other and ill-defined sites).

MALIGNANT NEOPLASM OF LIP, ORAL CAVITY, AND PHARYNX (140-149)

Excludes:	carcinoma in situ (230.0)
140	Malignant neoplasm of lip
Excludes:	skin of lip (173.0)
140.0	Upper lip, vermilion border
Upper lip:
NOS
external
lipstick area
140.1	Lower lip, vermilion border
Lower lip:
NOS
external
lipstick area
140.3	Upper lip, inner aspect
Upper lip:
buccal aspect
frenulum
mucosa
oral aspect
140.4	Lower lip, inner aspect
Lower lip:
buccal aspect
frenulum
mucosa
oral aspect
140.5	Lip, unspecified, inner aspect
Lip, not specified whether upper or lower:
buccal aspect
frenulum
mucosa
oral aspect
140.6	Commissure of lip
Labial commissure
140.8	Other sites of lip
Malignant neoplasm of contiguous or overlapping sites of lip whose point of origin cannot be
 determined
140.9	Lip, unspecified, vermilion border
Lip, not specified as upper or lower:
NOS
external
lipstick area
141	Malignant neoplasm of tongue
141.0	Base of tongue
Dorsal surface of base of tongue
Fixed part of tongue NOS
141.1	Dorsal surface of tongue
Anterior two-thirds of tongue, dorsal surface
Dorsal tongue NOS
Midline of tongue
Excludes:	dorsal surface of base of tongue (141.0)
141.2	Tip and lateral border of tongue
141.3	Ventral surface of tongue
Anterior two-thirds of tongue, ventral surface
Frenulum linguae
141.4	Anterior two-thirds of tongue, part unspecified
Mobile part of tongue NOS
141.5	Junctional zone
Border of tongue at junction of fixed and mobile parts at insertion of anterior tonsillar pillar
141.6	Lingual tonsil
141.8	Other sites of tongue
Malignant neoplasm of contiguous or overlapping sites of tongue whose point of origin cannot be
 determined
141.9	Tongue, unspecified
Tongue NOS
142	Malignant neoplasm of major salivary glands
Includes:	salivary ducts
Excludes:	malignant neoplasm of minor salivary glands:
NOS (145.9)
buccal mucosa (145.0)
soft palate (145.3)
tongue (141.0-141.9)
tonsil, palatine (146.0)
142.0	Parotid gland
142.1	Submandibular gland
Submaxillary gland
142.2	Sublingual gland
142.8	Other major salivary glands
Malignant neoplasm of contiguous or overlapping sites of salivary glands and ducts whose point
 of origin cannot be determined
142.9	Salivary gland, unspecified
Salivary gland (major) NOS
143	Malignant neoplasm of gum
Includes:	alveolar (ridge) mucosa
gingiva (alveolar) (marginal)
interdental papillae
Excludes:	malignant odontogenic neoplasms (170.0-170.1)
143.0	Upper gum
143.1	Lower gum
143.8	Other sites of gum
Malignant neoplasm of contiguous or overlapping sites of gum whose point of origin cannot be
 determined
143.9	Gum, unspecified
144	Malignant neoplasm of floor of mouth
144.0	Anterior portion
Anterior to the premolar-canine junction
144.1	Lateral portion
144.8	Other sites of floor of mouth
Malignant neoplasm of contiguous or overlapping sites of floor of mouth whose point of origin
 cannot be determined
144.9	Floor of mouth, part unspecified
145	Malignant neoplasm of other and unspecified parts of mouth
Excludes:	mucosa of lips (140.0-140.9)
145.0	Cheek mucosa
Buccal mucosa
Cheek, inner aspect
145.1	Vestibule of mouth
Buccal sulcus (upper) (lower)
Labial sulcus (upper) (lower)
145.2	Hard palate
145.3	Soft palate
Excludes:	nasopharyngeal [posterior] [superior] surface of soft palate (147.3)
145.4	Uvula
145.5	Palate, unspecified
Junction of hard and soft palate
Roof of mouth
145.6	Retromolar area
145.8	Other specified parts of mouth
Malignant neoplasm of contiguous or overlapping sites of mouth whose point of origin cannot be
 determined
145.9	Mouth, unspecified
Buccal cavity NOS
Minor salivary gland, unspecified site
Oral cavity NOS
146	Malignant neoplasm of oropharynx
146.0	Tonsil
Tonsil:
NOS
faucial
palatine
Excludes:	lingual tonsil (141.6)
pharyngeal tonsil (147.1)
146.1	Tonsillar fossa
146.2	Tonsillar pillars (anterior) (posterior)
Faucial pillar
Glossopalatine fold
Palatoglossal arch
Palatopharyngeal arch
146.3	Vallecula
Anterior and medial surface of the pharyngoepiglottic fold
146.4	Anterior aspect of epiglottis
Epiglottis, free border [margin]
Glossoepiglottic fold(s)
Excludes:	epiglottis:
NOS (161.1)
suprahyoid portion (161.1)
146.5	Junctional region
Junction of the free margin of the epiglottis, the aryepiglottic fold, and the
 pharyngoepiglottic fold
146.6	Lateral wall of oropharynx
146.7	Posterior wall of oropharynx
146.8	Other specified sites of oropharynx
Branchial cleft
Malignant neoplasm of contiguous or overlapping sites of oropharynx whose point of origin
 cannot be determined
146.9	Oropharynx, unspecified
147	Malignant neoplasm of nasopharynx
147.0	Superior wall
Roof of nasopharynx
147.1	Posterior wall
Adenoid
Pharyngeal tonsil
147.2	Lateral wall
Fossa of Rosenm�ller
Opening of auditory tube
Pharyngeal recess
147.3	Anterior wall
Floor of nasopharynx
Nasopharyngeal [posterior] [superior] surface of soft palate
Posterior margin of nasal septum and choanae
147.8	Other specified sites of nasopharynx
Malignant neoplasm of contiguous or overlapping sites of nasopharynx whose point of origin
 cannot be determined
147.9	Nasopharynx, unspecified
Nasopharyngeal wall NOS
148	Malignant neoplasm of hypopharynx
148.0	Postcricoid region
148.1	Pyriform sinus
Pyriform fossa
148.2	Aryepiglottic fold, hypopharyngeal aspect
Aryepiglottic fold or interarytenoid fold:
NOS
marginal zone
Excludes:	aryepiglottic fold or interarytenoid fold, laryngeal aspect (161.1)
148.3	Posterior hypopharyngeal wall
148.8	Other specified sites of hypopharynx
Malignant neoplasm of contiguous or overlapping sites of hypopharynx whose point of origin
 cannot be determined
148.9	Hypopharynx, unspecified
Hypopharyngeal wall NOS
Hypopharynx NOS
149	Malignant neoplasm of other and ill-defined sites within the lip, oral cavity, and
 pharynx
149.0	Pharynx, unspecified
149.1	Waldeyer's ring
149.8	Other
Malignant neoplasms of lip, oral cavity, and pharynx whose point of origin cannot be assigned
 to any one of the categories 140-148
Excludes:	"book leaf" neoplasm [ventral surface of tongue and floor of mouth] (145.8)
149.9	Ill-defined

MALIGNANT NEOPLASM OF DIGESTIVE ORGANS AND PERITONEUM (150-159)

Excludes:	carcinoma in situ (230.1-230.9)
150	Malignant neoplasm of esophagus
150.0	Cervical esophagus
150.1	Thoracic esophagus
150.2	Abdominal esophagus
Excludes:	adenocarcinoma (151.0)
cardio-esophageal junction (151.0)
150.3	Upper third of esophagus
Proximal third of esophagus
150.4	Middle third of esophagus
150.5	Lower third of esophagus
Distal third of esophagus
Excludes:	adenocarcinoma (151.0)
cardio-esophageal junction (151.0)
150.8	Other specified part
Malignant neoplasm of contiguous or overlapping sites of esophagus whose point of origin cannot
 be determined
150.9	Esophagus, unspecified
151	Malignant neoplasm of stomach
Excludes:	malignant stromal tumor of stomach (171.5)
151.0	Cardia
Cardiac orifice
Cardio-esophageal junction
Excludes:	squamous cell carcinoma (150.2, 150.5)
151.1	Pylorus
Prepylorus
Pyloric canal
151.2	Pyloric antrum
Antrum of stomach NOS
151.3	Fundus of stomach
151.4	Body of stomach
151.5	Lesser curvature, unspecified
Lesser curvature, not classifiable to 151.1-151.4
151.6	Greater curvature, unspecified
Greater curvature, not classifiable to 151.0-151.4
151.8	Other specified sites of stomach
Anterior wall, not classifiable to 151.0-151.4
Posterior wall, not classifiable to 151.0-151.4
Malignant neoplasm of contiguous or overlapping sites of stomach whose point of origin cannot
 be determined
151.9	Stomach, unspecified
Carcinoma ventriculi
Gastric cancer
152	Malignant neoplasm of small intestine, including duodenum
Excludes:	malignant stromal tumor of small intestine (171.5)
152.0	Duodenum
152.1	Jejunum
152.2	Ileum
Excludes:	ileocecal valve (153.4)
152.3	Meckel's diverticulum
152.8	Other specified sites of small intestine
Duodenojejunal junction
Malignant neoplasm of contiguous or overlapping sites of small intestine whose point of origin
 cannot be determined
152.9	Small intestine, unspecified
153	Malignant neoplasm of colon
153.0	Hepatic flexure
153.1	Transverse colon
153.2	Descending colon
Left colon
153.3	Sigmoid colon
Sigmoid (flexure)
Excludes:	rectosigmoid junction (154.0)
153.4	Cecum
Ileocecal valve
153.5	Appendix
153.6	Ascending colon
Right colon
153.7	Splenic flexure
153.8	Other specified sites of large intestine
Malignant neoplasm of contiguous or overlapping sites of colon whose point of origin cannot be
 determined
Excludes:	ileocecal valve (153.4)
rectosigmoid junction (154.0)
153.9	Colon, unspecified
Large intestine NOS
154	Malignant neoplasm of rectum, rectosigmoid junction, and anus
154.0	Rectosigmoid junction
Colon with rectum
Rectosigmoid (colon)
154.1	Rectum
Rectal ampulla
154.2	Anal canal
Anal sphincter
Excludes:	skin of anus (172.5, 173.5)
154.3	Anus, unspecified
Excludes:	anus:
margin (172.5, 173.5)
skin (172.5, 173.5)
perianal skin (172.5, 173.5)
154.8	Other
Anorectum
Cloacogenic zone
Malignant neoplasm of contiguous or overlapping sites of rectum, rectosigmoid junction, and
 anus whose point of origin cannot be determined
155	Malignant neoplasm of liver and intrahepatic bile ducts
155.0	Liver, primary
Carcinoma:
liver, specified as primary
hepatocellular
liver cell
Hepatoblastoma
155.1	Intrahepatic bile ducts
Canaliculi biliferi
Interlobular:
bile ducts
biliary canals
Intrahepatic:
biliary passages
canaliculi
gall duct
Excludes:	hepatic duct (156.1)
155.2	Liver, not specified as primary or secondary
156	Malignant neoplasm of gallbladder and extrahepatic bile ducts
156.0	Gallbladder
156.1	Extrahepatic bile ducts
Biliary duct or passage
NOS
Common bile duct
Cystic duct
Hepatic duct
Sphincter of Oddi
156.2	Ampulla of Vater
156.8	Other specified sites of gallbladder and extrahepatic bile ducts
Malignant neoplasm of contiguous or overlapping sites of gallbladder and extrahepatic bile
 ducts whose point of origin cannot be determined
156.9	Biliary tract, part unspecified
Malignant neoplasm involving both intrahepatic and extrahepatic bile ducts
157	Malignant neoplasm of pancreas
157.0	Head of pancreas
157.1	Body of pancreas
157.2	Tail of pancreas
157.3	Pancreatic duct
Duct of:
Santorini
Wirsung
157.4	Islets of Langerhans
Islets of Langerhans, any part of pancreas
Use additional code to identify any functional activity
157.8	Other specified sites of pancreas
Ectopic pancreatic tissue
Malignant neoplasm of contiguous or overlapping sites of pancreas whose point of origin cannot
 be determined
157.9	Pancreas, part unspecified
158	Malignant neoplasm of retroperitoneum and peritoneum
158.0	Retroperitoneum
Periadrenal tissue
Perinephric tissue
Perirenal tissue
Retrocecal tissue
158.8	Specified parts of peritoneum
Cul-de-sac (of Douglas)
Mesentery
Mesocolon
Omentum
Peritoneum:
parietal
pelvic
Rectouterine pouch
Malignant neoplasm of contiguous or overlapping sites of retroperitoneum and peritoneum whose
 point of origin cannot be determined
158.9	Peritoneum, unspecified
159	Malignant neoplasm of other and ill-defined sites within the digestive organs and
 peritoneum
159.0	Intestinal tract, part unspecified
Intestine NOS
159.1	Spleen, not elsewhere classified
Angiosarcoma of spleen
Fibrosarcoma of spleen
Excludes:	Hodgkin's disease (201.0-201.9)
lymphosarcoma (200.1)
reticulosarcoma (200.0)
159.8	Other sites of digestive system and intra-abdominal organs
Malignant neoplasm of digestive organs and peritoneum whose point of origin cannot be assigned
 to any one of the categories 150-158
Excludes:	anus and rectum (154.8)
cardio-esophageal junction (151.0)
colon and rectum (154.0)
159.9	Ill-defined
Alimentary canal or tract NOS
Gastrointestinal tract NOS
Excludes:	abdominal NOS (195.2)
intra-abdominal NOS (195.2)

MALIGNANT NEOPLASM OF RESPIRATORY AND INTRATHORACIC ORGANS (160-165)

Excludes:	carcinoma in situ (231.0-231.9)
160	Malignant neoplasm of nasal cavities, middle ear, and accessory sinuses
160.0	Nasal cavities
Cartilage of nose
Conchae, nasal
Internal nose
Septum of nose
Vestibule of nose
Excludes:	nasal bone (170.0)
nose NOS (195.0)
olfactory bulb (192.0)
posterior margin of septum and choanae (147.3)
skin of nose (172.3, 173.3)
turbinates (170.0)
160.1	Auditory tube, middle ear, and mastoid air cells
Antrum tympanicum
Eustachian tube
Tympanic cavity
Excludes:	auditory canal (external) (172.2, 173.2)
bone of ear (meatus) (170.0)
cartilage of ear (171.0)
ear (external) (skin) (172.2, 173.2)
160.2	Maxillary sinus
Antrum (Highmore) (maxillary)
160.3	Ethmoidal sinus
160.4	Frontal sinus
160.5	Sphenoidal sinus
160.8	Other
Malignant neoplasm of contiguous or overlapping sites of nasal cavities, middle ear, and
 accessory sinuses whose point of origin cannot be determined
160.9	Accessory sinus, unspecified
161	Malignant neoplasm of larynx
161.0	Glottis
Intrinsic larynx
Laryngeal commissure (anterior) (posterior)
True vocal cord
Vocal cord NOS
161.1	Supraglottis
Aryepiglottic fold or interarytenoid fold, laryngeal aspect
Epiglottis (suprahyoid portion) NOS
Extrinsic larynx
False vocal cords
Posterior (laryngeal) surface of epiglottis
Ventricular bands
Excludes:	anterior aspect of epiglottis (146.4)
aryepiglottic fold or interarytenoid fold:
NOS (148.2)
hypopharyngeal aspect (148.2)
marginal zone (148.2)
161.2	Subglottis
161.3	Laryngeal cartilages
Cartilage:
arytenoid
cricoid
cuneiform
thyroid
161.8	Other specified sites of larynx
Malignant neoplasm of contiguous or overlapping sites of larynx whose point of origin cannot
 be determined
161.9	Larynx, unspecified
162	Malignant neoplasm of trachea, bronchus, and lung
162.0	Trachea
Cartilage of trachea
Mucosa of trachea
162.2	Main bronchus
Carina
Hilus of lung
162.3	Upper lobe, bronchus or lung
162.4	Middle lobe, bronchus or lung
162.5	Lower lobe, bronchus or lung
162.8	Other parts of bronchus or lung
Malignant neoplasm of contiguous or overlapping sites of bronchus or lung whose point of origin
 cannot be determined
162.9	Bronchus and lung, unspecified
163	Malignant neoplasm of pleura
163.0	Parietal pleura
163.1	Visceral pleura
163.8	Other specified sites of pleura
Malignant neoplasm of contiguous or overlapping sites of pleura whose point of origin cannot
 be determined
163.9	Pleura, unspecified
164	Malignant neoplasm of thymus, heart, and mediastinum
164.0	Thymus
164.1	Heart
Endocardium
Epicardium
Myocardium
Pericardium
Excludes:	great vessels (171.4)
164.2	Anterior mediastinum
164.3	Posterior mediastinum
164.8	Other
Malignant neoplasm of contiguous or overlapping sites of thymus, heart, and mediastinum whose
 point of origin cannot be determined
164.9	Mediastinum, part unspecified
165	Malignant neoplasm of other and ill-defined sites within the respiratory system and
 intrathoracic organs
165.0	Upper respiratory tract, part unspecified
165.8	Other
Malignant neoplasm of respiratory and intrathoracic organs whose point of origin cannot be
 assigned to any one of the categories 160-164
165.9	Ill-defined sites within the respiratory system
Respiratory tract NOS
Excludes:	intrathoracic NOS (195.1)
thoracic NOS (195.1)

MALIGNANT NEOPLASM OF BONE, CONNECTIVE TISSUE, SKIN, AND BREAST (170-176)

Excludes:	carcinoma in situ:
breast (233.0)
skin (232.0-232.9)
170	Malignant neoplasm of bone and articular cartilage
Includes:	cartilage (articular) (joint)
periosteum
Excludes:	bone marrow NOS (202.9)
cartilage:
ear (171.0)
eyelid (171.0)
larynx (161.3)
nose (160.0)
synovia (171.0-171.9)
170.0	Bones of skull and face, except mandible
Bone:
ethmoid
frontal
malar
nasal
occipital
orbital
parietal
sphenoid
temporal
zygomatic
Maxilla (superior)
Turbinate
Upper jaw bone
Vomer
Excludes:	carcinoma, any type except intraosseous or odontogenic:
maxilla, maxillary (sinus) (160.2)
upper jaw bone (143.0)
jaw bone (lower) (170.1)
170.1	Mandible
Inferior maxilla
Jaw bone NOS
Lower jaw bone
Excludes:	carcinoma, any type except intraosseous or odontogenic:
jaw bone NOS (143.9)
lower (143.1)
upper jaw bone (170.0)
170.2	Vertebral column, excluding sacrum and coccyx
Spinal column
Spine
Vertebra
Excludes:	sacrum and coccyx (170.6)
170.3	Ribs, sternum, and clavicle
Costal cartilage
Costovertebral joint
Xiphoid process
170.4	Scapula and long bones of upper limb
Acromion
Bones NOS of upper limb
Humerus
Radius
Ulna
170.5	Short bones of upper limb
Carpal
Cuneiform, wrist
Metacarpal
Navicular, of hand
Phalanges of hand
Pisiform
Scaphoid (of hand)
Semilunar or lunate
Trapezium
Trapezoid
Unciform
170.6	Pelvic bones, sacrum, and coccyx
Coccygeal vertebra
Ilium
Ischium
Pubic bone
Sacral vertebra
170.7	Long bones of lower limb
Bones NOS of lower limb
Femur
Fibula
Tibia
170.8	Short bones of lower limb
Astragalus [talus]
Calcaneus
Cuboid
Cuneiform, ankle
Metatarsal
Navicular (of ankle)
Patella
Phalanges of foot
Tarsal
170.9	Bone and articular cartilage, site unspecified
171	Malignant neoplasm of connective and other soft tissue
Includes:	blood vessel
bursa
fascia
fat
ligament, except uterine
malignant stromal tumors
muscle
peripheral, sympathetic, and parasympathetic nerves and ganglia
synovia
tendon (sheath)
Excludes:	cartilage (of):
articular (170.0-170.9)
larynx (161.3)
nose (160.0)
connective tissue:
breast (174.0-175.9)
internal organs (except stromal tumors) � code to malignant neoplasm of the site [e.g.,
 leiomyosarcoma of stomach, 151.9]
heart (164.1)
uterine ligament (183.4)
171.0	Head, face, and neck
Cartilage of:
ear
eyelid
171.2	Upper limb, including shoulder
Arm
Finger
Forearm
Hand
171.3	Lower limb, including hip
Foot
Leg
Popliteal space
Thigh
Toe
171.4	Thorax
Axilla
Diaphragm
Great vessels
Excludes:	heart (164.1)
mediastinum (164.2-164.9)
thymus (164.0)
171.5	Abdomen
Abdominal wall
Hypochondrium
Excludes:	peritoneum (158.8)
retroperitoneum (158.0)
171.6	Pelvis
Buttock
Groin
Inguinal region
Perineum
Excludes:	pelvic peritoneum (158.8)
retroperitoneum (158.0)
uterine ligament, any (183.3-183.5)
171.7	Trunk, unspecified
Back NOS
Flank NOS
171.8	Other specified sites of connective and other soft tissue
Malignant neoplasm of contiguous or overlapping sites of connective tissue whose point of
 origin cannot be determined
171.9	Connective and other soft tissue, site unspecified
172	Malignant melanoma of skin
Includes:	melanocarcinoma
melanoma (skin) NOS
Excludes:	skin of genital organs (184.0-184.9, 187.1-187.9)
sites other than skin�code to malignant neoplasm of the site
172.0	Lip
Excludes:	vermilion border of lip (140.0-140.1, 140.9)
172.1	Eyelid, including canthus
172.2	Ear and external auditory canal
Auricle (ear)
Auricular canal, external
External [acoustic] meatus
Pinna
172.3	Other and unspecified parts of face
Cheek (external)
Chin
Eyebrow
Forehead
Nose, external
Temple
172.4	Scalp and neck
172.5	Trunk, except scrotum
Axilla
Breast
Buttock
Groin
Perianal skin
Perineum
Umbilicus
Excludes:	anal canal (154.2)
anus NOS (154.3)
scrotum (187.7)
172.6	Upper limb, including shoulder
Arm
Finger
Forearm
Hand
172.7	Lower limb, including hip
Ankle
Foot
Heel
Knee
Leg
Popliteal area
Thigh
Toe
172.8	Other specified sites of skin
Malignant melanoma of contiguous or overlapping sites of skin whose point of origin cannot be
 determined
172.9	Melanoma of skin, site unspecified
173	Other malignant neoplasm of skin
Includes:	malignant neoplasm of:
sebaceous glands
sudoriferous, sudoriparous glands
sweat glands
Excludes:	Kaposi's sarcoma (176.0-176.9)
malignant melanoma of skin (172.0-172.9)
skin of genital organs (184.0-184.9, 187.1-187.9)
173.0	Skin of lip
Excludes:	vermilion border of lip (140.0-140.1, 140.9)
173.1	Eyelid, including canthus
Excludes:	cartilage of eyelid (171.0)
173.2	Skin of ear and external auditory canal
Auricle (ear)
Auricular canal, external
External meatus
Pinna
Excludes:	cartilage of ear (171.0)
173.3	Skin of other and unspecified parts of face
Cheek, external
Chin
Eyebrow
Forehead
Nose, external
Temple
173.4	Scalp and skin of neck
173.5	Skin of trunk, except scrotum
Axillary fold
Perianal skin
Skin of:
abdominal wall
anus
back
breast
buttock
chest wall
groin
perineum
Umbilicus
Excludes:	anal canal (154.2)
anus NOS (154.3)
skin of scrotum (187.7)
173.6	Skin of upper limb, including shoulder
Arm
Finger
Forearm
Hand
173.7	Skin of lower limb, including hip
Ankle
Foot
Heel
Knee
Leg
Popliteal area
Thigh
Toe
173.8	Other specified sites of skin
Malignant neoplasm of contiguous or overlapping sites of skin whose point of origin cannot be
 determined
173.9	Skin, site unspecified
174	Malignant neoplasm of female breast
Includes:	breast (female)
connective tissue
soft parts
Paget's disease of:
breast
nipple
Use additional code to identify estrogen receptor status (V86.0, V86.1)
Excludes:	skin of breast (172.5, 173.5)
174.0	Nipple and areola
174.1	Central portion
174.2	Upper-inner quadrant
174.3	Lower-inner quadrant
174.4	Upper-outer quadrant
174.5	Lower-outer quadrant
174.6	Axillary tail
174.8	Other specified sites of female breast
Ectopic sites
Inner breast
Lower breast
Midline of breast
Outer breast
Upper breast
Malignant neoplasm of contiguous or overlapping sites of breast whose point of origin cannot
 be determined
174.9	Breast (female), unspecified
175	Malignant neoplasm of male breast
Use additional code to identify estrogen receptor status (V86.0, V86.1)
Excludes:	skin of breast (172.5, 173.5)
175.0	Nipple and areola
175.9	Other and unspecified sites of male breast
Ectopic breast tissue, male
176	Kaposi's sarcoma
176.0	Skin
176.1	Soft tissue
Blood vessel
Connective tissue
Fascia
Ligament
Lymphatic(s) NEC
Muscle
Excludes:	lymph glands and nodes (176.5)
176.2	Palate
176.3	Gastrointestinal sites
176.4	Lung
176.5	Lymph nodes
176.8	Other specified sites
Oral cavity NEC
176.9	Unspecified
Viscera NOS

MALIGNANT NEOPLASM OF GENITOURINARY ORGANS (179-189)

Excludes:	carcinoma in situ (233.1-233.9)
179	Malignant neoplasm of uterus, part unspecified
180	Malignant neoplasm of cervix uteri
Includes:	invasive malignancy [carcinoma]
Excludes:	carcinoma in situ (233.1)
180.0	Endocervix
Cervical canal NOS
Endocervical canal
Endocervical gland
180.1	Exocervix
180.8	Other specified sites of cervix
Cervical stump
Squamocolumnar junction of cervix
Malignant neoplasm of contiguous or overlapping sites of cervix uteri whose point of origin
 cannot be determined
180.9	Cervix uteri, unspecified
181	Malignant neoplasm of placenta
Choriocarcinoma NOS
Chorioepithelioma NOS
Excludes:	chorioadenoma (destruens) (236.1)
hydatidiform mole (630)
malignant (236.1)
invasive mole (236.1)
male choriocarcinoma NOS (186.0-186.9)
182	Malignant neoplasm of body of uterus
Excludes:	carcinoma in situ (233.2)
182.0	Corpus uteri, except isthmus
Cornu
Endometrium
Fundus
Myometrium
182.1	Isthmus
Lower uterine segment
182.8	Other specified sites of body of uterus
Malignant neoplasm of contiguous or overlapping sites of body of uterus whose point of origin
 cannot be determined
Excludes:	uterus NOS (179)
183	Malignant neoplasm of ovary and other uterine adnexa
Excludes:	Douglas' cul-de-sac (158.8)
183.0	Ovary
Use additional code to identify any functional activity
183.2	Fallopian tube
Oviduct
Uterine tube
183.3	Broad ligament
Mesovarium
Parovarian region
183.4	Parametrium
Uterine ligament NOS
Uterosacral ligament
183.5	Round ligament
183.8	Other specified sites of uterine adnexa
Tubo-ovarian
Utero-ovarian
Malignant neoplasm of contiguous or overlapping sites of ovary and other uterine adnexa whose
 point of origin cannot be determined
183.9	Uterine adnexa, unspecified
184	Malignant neoplasm of other and unspecified female genital organs
Excludes:	carcinoma in situ (233.30-233.39)
184.0	Vagina
Gartner's duct
Vaginal vault
184.1	Labia majora
Greater vestibular [Bartholin's] gland
184.2	Labia minora
184.3	Clitoris
184.4	Vulva, unspecified
External female genitalia NOS
Pudendum
184.8	Other specified sites of female genital organs
Malignant neoplasm of contiguous or overlapping sites of female genital organs whose point
 of origin cannot be determined
184.9	Female genital organ, site unspecified
Female genitourinary tract NOS
185	Malignant neoplasm of prostate
Excludes:	seminal vesicles (187.8)
186	Malignant neoplasm of testis
Use additional code to identify any functional activity
186.0	Undescended testis
Ectopic testis
Retained testis
186.9	Other and unspecified testis
Testis:
NOS
descended
scrotal
187	Malignant neoplasm of penis and other male genital organs
187.1	Prepuce
Foreskin
187.2	Glans penis
187.3	Body of penis
Corpus cavernosum
187.4	Penis, part unspecified
Skin of penis NOS
187.5	Epididymis
187.6	Spermatic cord
Vas deferens
187.7	Scrotum
Skin of scrotum
187.8	Other specified sites of male genital organs
Seminal vesicle
Tunica vaginalis
Malignant neoplasm of contiguous or overlapping sites of penis and other male genital organs
 whose point of origin cannot be determined
187.9	Male genital organ, site unspecified
Male genital organ or tract NOS
188	Malignant neoplasm of bladder
Excludes:	carcinoma in situ (233.7)
188.0	Trigone of urinary bladder
188.1	Dome of urinary bladder
188.2	Lateral wall of urinary bladder
188.3	Anterior wall of urinary bladder
188.4	Posterior wall of urinary bladder
188.5	Bladder neck
Internal urethral orifice
188.6	Ureteric orifice
188.7	Urachus
188.8	Other specified sites of bladder
Malignant neoplasm of contiguous or overlapping sites of bladder whose point of origin cannot
 be determined
188.9	Bladder, part unspecified
Bladder wall NOS
189	Malignant neoplasm of kidney and other and unspecified urinary organs
189.0	Kidney, except pelvis
Kidney NOS
Kidney parenchyma
189.1	Renal pelvis
Renal calyces
Ureteropelvic junction
189.2	Ureter
Excludes:	ureteric orifice of bladder (188.6)
189.3	Urethra
Excludes:	urethral orifice of bladder (188.5)
189.4	Paraurethral glands
189.8	Other specified sites of urinary organs
Malignant neoplasm of contiguous or overlapping sites of kidney and other urinary organs
 whose point of origin cannot be determined
189.9	Urinary organ, site unspecified
Urinary system NOS

MALIGNANT NEOPLASM OF OTHER AND UNSPECIFIED SITES (190-199)

Excludes:	carcinoma in situ (234.0-234.9)
190	Malignant neoplasm of eye
Excludes:	carcinoma in situ (234.0)
eyelid (skin) (172.1, 173.1)
cartilage (171.0)
optic nerve (192.0)
orbital bone (170.0)
190.0	Eyeball, except conjunctiva, cornea, retina, and choroid
Ciliary body
Crystalline lens
Iris
Sclera
Uveal tract
190.1	Orbit
Connective tissue of orbit
Extraocular muscle
Retrobulbar
Excludes:	bone of orbit (170.0)
190.2	Lacrimal gland
190.3	Conjunctiva
190.4	Cornea
190.5	Retina
190.6	Choroid
190.7	Lacrimal duct
Lacrimal sac
Nasolacrimal duct
190.8	Other specified sites of eye
Malignant neoplasm of contiguous or overlapping sites of eye whose point of origin cannot
 be determined
190.9	Eye, part unspecified
191	Malignant neoplasm of brain
Excludes:	cranial nerves (192.0)
retrobulbar area (190.1)
191.0	Cerebrum, except lobes and ventricles
Basal ganglia
Cerebral cortex
Corpus striatum
Globus pallidus
Hypothalamus
Thalamus
191.1	Frontal lobe
191.2	Temporal lobe
Hippocampus
Uncus
191.3	Parietal lobe
191.4	Occipital lobe
191.5	Ventricles
Choroid plexus
Floor of ventricle
191.6	Cerebellum NOS
Cerebellopontine angle
191.7	Brain stem
Cerebral peduncle
Medulla oblongata
Midbrain
Pons
191.8	Other parts of brain
Corpus callosum
Tapetum
Malignant neoplasm of contiguous or overlapping sites of brain whose point of origin cannot
 be determined
191.9	Brain, unspecified
Cranial fossa NOS
192	Malignant neoplasm of other and unspecified parts of nervous system
Excludes:	peripheral, sympathetic, and parasympathetic nerves and ganglia (171.0-171.9)
192.0	Cranial nerves
Olfactory bulb
192.1	Cerebral meninges
Dura (mater)
Falx (cerebelli) (cerebri)
Meninges NOS
Tentorium
192.2	Spinal cord
Cauda equina
192.3	Spinal meninges
192.8	Other specified sites of nervous system
Malignant neoplasm of contiguous or overlapping sites of other parts of nervous system whose
 point of origin cannot be determined
192.9	Nervous system, part unspecified
Nervous system (central) NOS
Excludes:	meninges NOS (192.1)
193	Malignant neoplasm of thyroid gland
Thyroglossal duct
Use additional code to identify any functional activity
194	Malignant neoplasm of other endocrine glands and related structures
Use additional code to identify any functional activity
Excludes:	islets of Langerhans (157.4)
ovary (183.0)
testis (186.0-186.9)
thymus (164.0)
194.0	Adrenal gland
Adrenal cortex
Adrenal medulla
Suprarenal gland
194.1	Parathyroid gland
194.3	Pituitary gland and craniopharyngeal duct
Craniobuccal pouch
Hypophysis
Rathke's pouch
Sella turcica
194.4	Pineal gland
194.5	Carotid body
194.6	Aortic body and other paraganglia
Coccygeal body
Glomus jugulare
Para-aortic body
194.8	Other
Pluriglandular involvement NOS
Note:	If the sites of multiple involvements are known, they should be coded separately.
194.9	Endocrine gland, site unspecified
195	Malignant neoplasm of other and ill-defined sites
Includes:	malignant neoplasms of contiguous sites, not elsewhere classified, whose
 point of origin cannot be determined
Excludes:	malignant neoplasm:
lymphatic and hematopoietic tissue (200.0-208.9)
secondary sites (196.0-198.8)
unspecified site (199.0-199.1)
195.0	Head, face, and neck
Cheek NOS
Jaw NOS
Nose NOS
Supraclavicular region NOS
195.1	Thorax
Axilla
Chest (wall) NOS
Intrathoracic NOS
195.2	Abdomen
Intra-abdominal NOS
195.3	Pelvis
Groin
Inguinal region NOS
Presacral region
Sacrococcygeal region
Sites overlapping systems within pelvis, as:
rectovaginal (septum)
rectovesical (septum)
195.4	Upper limb
195.5	Lower limb
195.8	Other specified sites
Back NOS
Flank NOS
Trunk NOS
196	Secondary and unspecified malignant neoplasm of lymph nodes
Excludes:	any malignant neoplasm of lymph nodes, specified as primary (200.0-202.9)
Hodgkin's disease (201.0-201.9)
lymphosarcoma (200.1)
reticulosarcoma (200.0)
other forms of lymphoma (202.0-202.9)
196.0	Lymph nodes of head, face, and neck
Cervical
Cervicofacial
Scalene
Supraclavicular
196.1	Intrathoracic lymph nodes
Bronchopulmonary
Intercostal
Mediastinal
Tracheobronchial
196.2	Intra-abdominal lymph nodes
Intestinal
Mesenteric
Retroperitoneal
196.3	Lymph nodes of axilla and upper limb
Brachial
Epitrochlear
Infraclavicular
Pectoral
196.5	Lymph nodes of inguinal region and lower limb
Femoral
Groin
Popliteal
Tibial
196.6	Intrapelvic lymph nodes
Hypogastric
Iliac
Obturator
Parametrial
196.8	Lymph nodes of multiple sites
196.9	Site unspecified
Lymph nodes NOS
197	Secondary malignant neoplasm of respiratory and digestive systems
Excludes:	lymph node metastasis (196.0-196.9)
197.0	Lung
Bronchus
197.1	Mediastinum
197.2	Pleura
197.3	Other respiratory organs
Trachea
197.4	Small intestine, including duodenum
197.5	Large intestine and rectum
197.6	Retroperitoneum and peritoneum
197.7	Liver, specified as secondary
197.8	Other digestive organs and spleen
198	Secondary malignant neoplasm of other specified sites
Excludes:	lymph node metastasis (196.0-196.9)
198.0	Kidney
198.1	Other urinary organs
198.2	Skin
Skin of breast
198.3	Brain and spinal cord
198.4	Other parts of nervous system
Meninges (cerebral) (spinal)
198.5	Bone and bone marrow
198.6	Ovary
198.7	Adrenal gland
Suprarenal gland
198.8	Other specified sites
198.81	Breast
Excludes:	skin of breast (198.2)
198.82	Genital organs
198.89	Other
Excludes:	retroperitoneal lymph nodes (196.2)
199	Malignant neoplasm without specification of site
199.0	Disseminated
Carcinomatosis unspecified site (primary) (secondary)
Generalized:
cancer unspecified site (primary) (secondary)
malignancy unspecified site (primary) (secondary)
Multiple cancer unspecified site (primary) (secondary)
199.1	Other
Cancer unspecified site (primary) (secondary)
Carcinoma unspecified site (primary) (secondary)
Malignancy unspecified site (primary) (secondary)

MALIGNANT NEOPLASM OF LYMPHATIC AND HEMATOPOIETIC TISSUE (200-208)

Excludes:	secondary neoplasm of:
bone marrow (198.5)
spleen (197.8)
secondary and unspecified neoplasm of lymph nodes (196.0-196.9)
The following fifth-digit subclassification is for use with categories 200-202:
0	unspecified site, extranodal and solid organ sites
1	lymph nodes of head, face, and neck
2	intrathoracic lymph nodes
3	intra-abdominal lymph nodes
4	lymph nodes of axilla and upper limb
5	lymph nodes of inguinal region and lower limb
6	intrapelvic lymph nodes
7	spleen
8	lymph nodes of multiple sites
200	Lymphosarcoma and reticulosarcoma and other specified malignant tumors of
 lymphatic  tissue
Requires fifth digit. See note before section 200 for codes and definitions.
200.0	Reticulosarcoma
Lymphoma (malignant):
histiocytic (diffuse):
nodular
pleomorphic cell type
reticulum cell type
Reticulum cell sarcoma:
NOS
pleomorphic cell type
200.1	Lymphosarcoma
Lymphoblastoma (diffuse)
Lymphoma (malignant):
lymphoblastic (diffuse)
lymphocytic (cell type) (diffuse)
lymphosarcoma type
Lymphosarcoma:
NOS
diffuse NOS
lymphoblastic (diffuse)
lymphocytic (diffuse)
prolymphocytic
Excludes:	lymphosarcoma:
follicular or nodular (202.0)
mixed cell type (200.8)
lymphosarcoma cell leukemia (207.8)
200.2	Burkitt's tumor or lymphoma
Malignant lymphoma, Burkitt's type
200.3	Marginal zone lymphoma
Extranodal marginal zone B cell lymphoma
Mucosa associated lymphoid tissue [MALT]
Nodal marginal zone B cell lymphoma
Splenic marginal zone B cell lymphoma
200.4	Mantle cell lymphoma
200.5	Primary central nervous system lymphoma
200.6	Anaplastic large cell lymphoma
200.7	Large cell lymphoma
200.8	Other named variants
Lymphoma (malignant):
lymphoplasmacytoid type
mixed lymphocytic-histiocytic (diffuse)
Lymphosarcoma, mixed cell type (diffuse)
Reticulolymphosarcoma (diffuse)
201	Hodgkin's disease
Requires fifth digit. See note before section 200 for codes and definitions.
201.0	Hodgkin's paragranuloma
201.1	Hodgkin's granuloma
201.2	Hodgkin's sarcoma
201.4	Lymphocytic-histiocytic predominance
201.5	Nodular sclerosis
Hodgkin's disease, nodular sclerosis:
NOS
cellular phase
201.6	Mixed cellularity
201.7	Lymphocytic depletion
Hodgkin's disease, lymphocytic depletion:
NOS
diffuse fibrosis
reticular type
201.9	Hodgkin's disease, unspecified
Hodgkin's:
disease NOS
lymphoma NOS
Malignant:
lymphogranuloma
lymphogranulomatosis
202	Other malignant neoplasms of lymphoid and histiocytic tissue
Requires fifth digit. See note before section 200 for codes and definitions.
202.0	Nodular lymphoma
Brill-Symmers disease
Lymphoma:
follicular (giant)
lymphocytic, nodular
Lymphosarcoma:
follicular (giant)
nodular
202.1	Mycosis fungoides
202.2	S�zary's disease
202.3	Malignant histiocytosis
Histiocytic medullary reticulosis
Malignant:
reticuloendotheliosis
reticulosis
202.4	Leukemic reticuloendotheliosis
Hairy-cell leukemia
202.5	Letterer-Siwe disease
Acute:
differentiated progressive histiocytosis
histiocytosis X (progressive)
infantile reticuloendotheliosis
reticulosis of infancy
Excludes:	Hand-Sch�ller-Christian disease (277.89)
histiocytosis (acute) (chronic) (277.89)
histiocytosis X (chronic) (277.89)
202.6	Malignant mast cell tumors
Malignant:
mastocytoma
mastocytosis
Mast cell sarcoma
Systemic tissue mast cell disease
Excludes:	mast cell leukemia (207.8)
202.7	Peripheral T cell lymphoma
202.8	Other lymphomas
Lymphoma (malignant):
NOS
diffuse
Excludes:	benign lymphoma (229.0)
202.9	Other and unspecified malignant neoplasms of lymphoid and histiocytic tissue
Follicular dendritic cell sarcoma
Interdigitating dendritic cell sarcoma
Langerhans cell sarcoma
Malignant neoplasm of bone marrow NOS
203	Multiple myeloma and immunoproliferative neoplasms
The following fifth-digit subclassification is for use with category 203:
0	without mention of remission
1	in remission
203.0	Multiple myeloma
Kahler's disease
Myelomatosis
Excludes:	solitary myeloma (238.6)
203.1	Plasma cell leukemia
Plasmacytic leukemia
203.8	Other immunoproliferative neoplasms
204	Lymphoid leukemia
Includes:	leukemia:
lymphatic
lymphoblastic
lymphocytic
lymphogenous
The following fifth-digit subclassification is for use with category 204:
0	without mention of remission
1	in remission
204.0	Acute
Excludes:	acute exacerbation of chronic lymphoid leukemia (204.1)
204.1	Chronic
204.2	Subacute
204.8	Other lymphoid leukemia
Aleukemic leukemia:
lymphatic
lymphocytic
lymphoid
204.9	Unspecified lymphoid leukemia
205	Myeloid leukemia
Includes:	leukemia:
granulocytic
myeloblastic
myelocytic
myelogenous
myelomonocytic
myelosclerotic
myelosis
The following fifth-digit subclassification is for use with category 205:
0	without mention of remission
1	in remission
205.0	Acute
Acute promyelocytic leukemia
Excludes:	acute exacerbation of chronic myeloid leukemia (205.1)
205.1	Chronic
Eosinophilic leukemia
Neutrophilic leukemia
205.2	Subacute
205.3	Myeloid sarcoma
Chloroma
Granulocytic sarcoma
205.8	Other myeloid leukemia
Aleukemic leukemia:
granulocytic
myelogenous
myeloid
Aleukemic myelosis
205.9	Unspecified myeloid leukemia
206	Monocytic leukemia
Includes:	leukemia:
histiocytic
monoblastic
monocytoid
The following fifth-digit subclassification is for use with category 206:
0	without mention of remission
1	in remission
206.0	Acute
Excludes:	acute exacerbation of chronic monocytic leukemia (206.1)
206.1	Chronic
206.2	Subacute
206.8	Other monocytic leukemia
Aleukemic:
monocytic leukemia
monocytoid leukemia
206.9	Unspecified monocytic leukemia
207	Other specified leukemia
Excludes:	leukemic reticuloendotheliosis (202.4)
plasma cell leukemia (203.1)
The following fifth-digit subclassification is for use with category 207:
0	without mention of remission
1	in remission
207.0	Acute erythremia and erythroleukemia
Acute erythremic myelosis
Di Guglielmo's disease
Erythremic myelosis
207.1	Chronic erythremia
Heilmeyer-Sch�ner disease
207.2	Megakaryocytic leukemia
Megakaryocytic myelosis
Thrombocytic leukemia
207.8	Other specified leukemia
Lymphosarcoma cell leukemia
208	Leukemia of unspecified cell type
The following fifth-digit subclassification is for use with category 208:
0	without mention of remission
1	in remission
208.0	Acute
Acute leukemia NOS
Blast cell leukemia
Stem cell leukemia
Excludes:	acute exacerbation of chronic unspecified leukemia (208.1)
208.1	Chronic
Chronic leukemia NOS
208.2	Subacute
Subacute leukemia NOS
208.8	Other leukemia of unspecified cell type
208.9	Unspecified leukemia
Leukemia NOS

BENIGN NEOPLASMS (210-229)

210	Benign neoplasm of lip, oral cavity, and pharynx
Excludes:	cyst (of):
jaw (526.0-526.2, 526.89)
oral soft tissue (528.4)
radicular (522.8)
210.0	Lip
Frenulum labii
Lip (inner aspect) (mucosa) (vermilion border)
Excludes:	labial commissure (210.4)
skin of lip (216.0)
210.1	Tongue
Lingual tonsil
210.2	Major salivary glands
Gland:
parotid
sublingual
submandibular
Excludes:	benign neoplasms of minor salivary glands:
NOS (210.4)
buccal mucosa (210.4)
lips (210.0)
palate (hard) (soft) (210.4)
tongue (210.1)
tonsil, palatine (210.5)
210.3	Floor of mouth
210.4	Other and unspecified parts of mouth
Gingiva
Gum (upper) (lower)
Labial commissure
Oral cavity NOS
Oral mucosa
Palate (hard) (soft)
Uvula
Excludes:	benign odontogenic neoplasms of bone (213.0-213.1)
developmental odontogenic cysts (526.0)
mucosa of lips (210.0)
nasopharyngeal [posterior] [superior] surface of soft palate (210.7)
210.5	Tonsil
Tonsil (faucial) (palatine)
Excludes:	lingual tonsil (210.1)
pharyngeal tonsil (210.7)
tonsillar:
fossa (210.6)
pillars (210.6)
210.6	Other parts of oropharynx
Branchial cleft or vestiges
Epiglottis, anterior aspect
Fauces NOS
Mesopharynx NOS
Tonsillar:
fossa
pillars
Vallecula
Excludes:	epiglottis:
NOS (212.1)
suprahyoid portion (212.1)
210.7	Nasopharynx
Adenoid tissue
Lymphadenoid tissue
Pharyngeal tonsil
Posterior nasal septum
210.8	Hypopharynx
Arytenoid fold
Laryngopharynx
Postcricoid region
Pyriform fossa
210.9	Pharynx, unspecified
Throat NOS
211	Benign neoplasm of other parts of digestive system
Excludes:	benign stromal tumors of digestive system (215.5)
211.0	Esophagus
211.1	Stomach
Body of stomach
Cardia of stomach
Fundus of stomach
Cardiac orifice
Pylorus
211.2	Duodenum, jejunum, and ileum
Small intestine NOS
Excludes:	ampulla of Vater (211.5)
ileocecal valve (211.3)
211.3	Colon
Appendix
Cecum
Ileocecal valve
Large intestine NOS
Excludes:	rectosigmoid junction (211.4)
211.4	Rectum and anal canal
Anal canal or sphincter
Anus NOS
Rectosigmoid junction
Excludes:	anus:
margin (216.5)
skin (216.5)
perianal skin (216.5)
211.5	Liver and biliary passages
Ampulla of Vater
Common bile duct
Cystic duct
Gallbladder
Hepatic duct
Sphincter of Oddi
211.6	Pancreas, except islets of Langerhans
211.7	Islets of Langerhans
Islet cell tumor
Use additional code to identify any functional activity
211.8	Retroperitoneum and peritoneum
Mesentery
Mesocolon
Omentum
Retroperitoneal tissue
211.9	Other and unspecified site
Alimentary tract NOS
Digestive system NOS
Gastrointestinal tract NOS
Intestinal tract NOS
Intestine NOS
Spleen, not elsewhere classified
212	Benign neoplasm of respiratory and intrathoracic organs
212.0	Nasal cavities, middle ear, and accessory sinuses
Cartilage of nose
Eustachian tube
Nares
Septum of nose
Sinus:
ethmoidal
frontal
maxillary
sphenoidal
Excludes:	auditory canal (external) (216.2)
bone of:
ear (213.0)
nose [turbinates] (213.0)
cartilage of ear (215.0)
ear (external) (skin) (216.2)
nose NOS (229.8)
skin (216.3)
olfactory bulb (225.1)
polyp of:
accessory sinus (471.8)
ear (385.30-385.35)
nasal cavity (471.0)
posterior margin of septum and choanae (210.7)
212.1	Larynx
Cartilage:
arytenoid
cricoid
cuneiform
thyroid
Epiglottis (suprahyoid portion) NOS
Glottis
Vocal cords (false) (true)
Excludes:	epiglottis, anterior aspect (210.6)
polyp of vocal cord or larynx (478.4)
212.2	Trachea
212.3	Bronchus and lung
Carina
Hilus of lung
212.4	Pleura
212.5	Mediastinum
212.6	Thymus
212.7	Heart
Excludes:	great vessels (215.4)
212.8	Other specified sites
212.9	Site unspecified
Respiratory organ NOS
Upper respiratory tract NOS
Excludes:	intrathoracic NOS (229.8)
thoracic NOS (229.8)
213	Benign neoplasm of bone and articular cartilage
Includes:	cartilage (articular) (joint)
periosteum
Excludes:	cartilage of:
ear (215.0)
eyelid (215.0)
larynx (212.1)
nose (212.0)
exostosis NOS (726.91)
synovia (215.0-215.9)
213.0	Bones of skull and face
Excludes:	lower jaw bone (213.1)
213.1	Lower jaw bone
213.2	Vertebral column, excluding sacrum and coccyx
213.3	Ribs, sternum, and clavicle
213.4	Scapula and long bones of upper limb
213.5	Short bones of upper limb
213.6	Pelvic bones, sacrum, and coccyx
213.7	Long bones of lower limb
213.8	Short bones of lower limb
213.9	Bone and articular cartilage, site unspecified
214	Lipoma
Includes:	angiolipoma
fibrolipoma
hibernoma
lipoma (fetal) (infiltrating) (intramuscular)
myelolipoma
myxolipoma
214.0	Skin and subcutaneous tissue of face
214.1	Other skin and subcutaneous tissue
214.2	Intrathoracic organs
214.3	Intra-abdominal organs
214.4	Spermatic cord
214.8	Other specified sites
214.9	Lipoma, unspecified site
215	Other benign neoplasm of connective and other soft tissue
Includes:	blood vessel
bursa
fascia
ligament
muscle
peripheral, sympathetic, and parasympathetic nerves and ganglia
synovia
tendon (sheath)
Excludes:	cartilage:
articular (213.0-213.9)
larynx (212.1)
nose (212.0)
connective tissue of:
breast (217)
internal organ, except lipoma and hemangioma�code to benign neoplasm of the site
lipoma (214.0-214.9)
215.0	Head, face, and neck
215.2	Upper limb, including shoulder
215.3	Lower limb, including hip
215.4	Thorax
Excludes:	heart (212.7)
mediastinum (212.5)
thymus (212.6)
215.5	Abdomen
Abdominal wall
Benign stromal tumors of abdomen
Hypochondrium
215.6	Pelvis
Buttock
Groin
Inguinal region
Perineum
Excludes:	uterine:
leiomyoma (218.0-218.9)
ligament, any (221.0)
215.7	Trunk, unspecified
Back NOS
Flank NOS
215.8	Other specified sites
215.9	Site unspecified
216	Benign neoplasm of skin
Includes:	blue nevus
dermatofibroma
hydrocystoma
pigmented nevus
syringoadenoma
syringoma
Excludes:	skin of genital organs (221.0-222.9)
216.0	Skin of lip
Excludes:	vermilion border of lip (210.0)
216.1	Eyelid, including canthus
Excludes:	cartilage of eyelid (215.0)
216.2	Ear and external auditory canal
Auricle (ear)
Auricular canal, external
External meatus
Pinna
Excludes:	cartilage of ear (215.0)
216.3	Skin of other and unspecified parts of face
Cheek, external
Eyebrow
Nose, external
Temple
216.4	Scalp and skin of neck
216.5	Skin of trunk, except scrotum
Axillary fold
Perianal skin
Skin of:
abdominal wall
anus
back
breast
buttock
chest wall
groin
perineum
Umbilicus
Excludes:	anal canal (211.4)
anus NOS (211.4)
skin of scrotum (222.4)
216.6	Skin of upper limb, including shoulder
216.7	Skin of lower limb, including hip
216.8	Other specified sites of skin
216.9	Skin, site unspecified
217	Benign neoplasm of breast
Breast (male) (female)
connective tissue
glandular tissue
soft parts
Excludes:	adenofibrosis (610.2)
benign cyst of breast (610.0)
fibrocystic disease (610.1)
skin of breast (216.5)
218	Uterine leiomyoma
Includes:	fibroid (bleeding) (uterine)
uterine:
fibromyoma
myoma
218.0	Submucous leiomyoma of uterus
218.1	Intramural leiomyoma of uterus
Interstitial leiomyoma of uterus
218.2	Subserous leiomyoma of uterus
Subperitoneal leiomyoma of uterus
218.9	Leiomyoma of uterus, unspecified
219	Other benign neoplasm of uterus
219.0	Cervix uteri
219.1	Corpus uteri
Endometrium
Fundus
Myometrium
219.8	Other specified parts of uterus
219.9	Uterus, part unspecified
220	Benign neoplasm of ovary
Use additional code to identify any functional activity (256.0-256.1)
Excludes:	cyst:
corpus albicans (620.2)
corpus luteum (620.1)
endometrial (617.1)
follicular (atretic) (620.0)
graafian follicle (620.0)
ovarian NOS (620.2)
retention (620.2)
221	Benign neoplasm of other female genital organs
Includes:	adenomatous polyp
benign teratoma
Excludes:	cyst:
epoophoron (752.11)
fimbrial (752.11)
Gartner's duct (752.11)
parovarian (752.11)
221.0	Fallopian tube and uterine ligaments
Oviduct
Parametrium
Uterine ligament (broad) (round) (uterosacral)
Uterine tube
221.1	Vagina
221.2	Vulva
Clitoris
External female genitalia NOS
Greater vestibular [Bartholin's] gland
Labia (majora) (minora)
Pudendum
Excludes:	Bartholin's (duct) (gland) cyst (616.2)
221.8	Other specified sites of female genital organs
221.9	Female genital organ, site unspecified
Female genitourinary tract NOS
222	Benign neoplasm of male genital organs
222.0	Testis
Use additional code to identify any functional activity
222.1	Penis
Corpus cavernosum
Glans penis
Prepuce
222.2	Prostate
Excludes:	adenomatous hyperplasia of prostate (600.20-600.21)
prostatic:
adenoma (600.20-600.21)
enlargement (600.00-600.01)
hypertrophy (600.00-600.01)
222.3	Epididymis
222.4	Scrotum
Skin of scrotum
222.8	Other specified sites of male genital organs
Seminal vesicle
Spermatic cord
222.9	Male genital organ, site unspecified
Male genitourinary tract NOS
223	Benign neoplasm of kidney and other urinary organs
223.0	Kidney, except pelvis
Kidney NOS
Excludes:	renal:
calyces (223.1)
pelvis (223.1)
223.1	Renal pelvis
223.2	Ureter
Excludes:	ureteric orifice of bladder (223.3)
223.3	Bladder
223.8	Other specified sites of urinary organs
223.81	Urethra
Excludes:	urethral orifice of bladder (223.3)
223.89	Other
Paraurethral glands
223.9	Urinary organ, site unspecified
Urinary system NOS
224	Benign neoplasm of eye
Excludes:	cartilage of eyelid (215.0)
eyelid (skin) (216.1)
optic nerve (225.1)
orbital bone (213.0)
224.0	Eyeball, except conjunctiva, cornea, retina, and choroid
Ciliary body
Iris
Sclera
Uveal tract
224.1	Orbit
Excludes:	bone of orbit (213.0)
224.2	Lacrimal gland
224.3	Conjunctiva
224.4	Cornea
224.5	Retina
Excludes:	hemangioma of retina (228.03)
224.6	Choroid
224.7	Lacrimal duct
Lacrimal sac
Nasolacrimal duct
224.8	Other specified parts of eye
224.9	Eye, part unspecified
225	Benign neoplasm of brain and other parts of nervous system
Excludes:	hemangioma (228.02)
neurofibromatosis (237.7)
peripheral, sympathetic, and parasympathetic nerves and ganglia (215.0-215.9)
retrobulbar (224.1)
225.0	Brain
225.1	Cranial nerves
225.2	Cerebral meninges
Meninges NOS
Meningioma (cerebral)
225.3	Spinal cord
Cauda equina
225.4	Spinal meninges
Spinal meningioma
225.8	Other specified sites of nervous system
225.9	Nervous system, part unspecified
Nervous system (central) NOS
Excludes:	meninges NOS (225.2)
226	Benign neoplasm of thyroid glands
Use additional code to identify any functional activity
227	Benign neoplasm of other endocrine glands and related structures
Use additional code to identify any functional activity
Excludes:	ovary (220)
pancreas (211.6)
testis (222.0)
227.0	Adrenal gland
Suprarenal gland
227.1	Parathyroid gland
227.3	Pituitary gland and craniopharyngeal duct (pouch)
Craniobuccal pouch
Hypophysis
Rathke's pouch
Sella turcica
227.4	Pineal gland
Pineal body
227.5	Carotid body
227.6	Aortic body and other paraganglia
Coccygeal body
Glomus jugulare
Para-aortic body
227.8	Other
227.9	Endocrine gland, site unspecified
228	Hemangioma and lymphangioma, any site
Includes:	angioma (benign) (cavernous) (congenital) NOS
cavernous nevus
glomus tumor
hemangioma (benign) (congenital)
Excludes:	benign neoplasm of spleen, except hemangioma and lymphangioma (211.9)
glomus jugulare (227.6)
nevus:
NOS (216.0-216.9)
blue or pigmented (216.0-216.9)
vascular (757.32)
228.0	Hemangioma, any site
228.00	Of unspecified site
228.01	Of skin and subcutaneous tissue
228.02	Of intracranial structures
228.03	Of retina
228.04	Of intra-abdominal structures
Peritoneum
Retroperitoneal tissue
228.09	Of other sites
Systemic angiomatosis
228.1	Lymphangioma, any site
Congenital lymphangioma
Lymphatic nevus
229	Benign neoplasm of other and unspecified sites
229.0	Lymph nodes
Excludes:	lymphangioma (228.1)
229.8	Other specified sites
Intrathoracic NOS
Thoracic NOS
229.9	Site unspecified

CARCINOMA IN SITU (230-234)

Includes:	Bowen's disease
erythroplasia
Queyrat's erythroplasia
Excludes:	leukoplakia�see Alphabetic Index
230	Carcinoma in situ of digestive organs
230.0	Lip, oral cavity, and pharynx
Gingiva
Hypopharynx
Mouth [any part]
Nasopharynx
Oropharynx
Salivary gland or duct
Tongue
Excludes:	aryepiglottic fold or interarytenoid fold, laryngeal aspect (231.0)
epiglottis:
NOS (231.0)
suprahyoid portion (231.0)
skin of lip (232.0)
230.1	Esophagus
230.2	Stomach
Body of stomach
Cardia of stomach
Fundus of stomach
Cardiac orifice
Pylorus
230.3	Colon
Appendix
Cecum
Ileocecal valve
Large intestine NOS
Excludes:	rectosigmoid junction (230.4)
230.4	Rectum
Rectosigmoid junction
230.5	Anal canal
Anal sphincter
230.6	Anus, unspecified
Excludes:	anus:
margin (232.5)
skin (232.5)
perianal skin (232.5)
230.7	Other and unspecified parts of intestine
Duodenum
Ileum
Jejunum
Small intestine NOS
Excludes:	ampulla of Vater (230.8)
230.8	Liver and biliary system
Ampulla of Vater
Common bile duct
Cystic duct
Gallbladder
Hepatic duct
Sphincter of Oddi
230.9	Other and unspecified digestive organs
Digestive organ NOS
Gastrointestinal tract NOS
Pancreas
Spleen
231	Carcinoma in situ of respiratory system
231.0	Larynx
Cartilage:
arytenoid
cricoid
cuneiform
thyroid
Epiglottis:
NOS
posterior surface
suprahyoid portion
Vocal cords (false) (true)
Excludes:	aryepiglottic fold or interarytenoid fold:
NOS (230.0)
hypopharyngeal aspect (230.0)
marginal zone (230.0)
231.1	Trachea
231.2	Bronchus and lung
Carina
Hilus of lung
231.8	Other specified parts of respiratory system
Accessory sinuses
Middle ear
Nasal cavities
Pleura
Excludes:	ear (external) (skin) (232.2)
nose NOS (234.8)
skin (232.3)
231.9	Respiratory system, part unspecified
Respiratory organ NOS
232	Carcinoma in situ of skin
Includes:	pigment cells
232.0	Skin of lip
Excludes:	vermilion border of lip (230.0)
232.1	Eyelid, including canthus
232.2	Ear and external auditory canal
232.3	Skin of other and unspecified parts of face
232.4	Scalp and skin of neck
232.5	Skin of trunk, except scrotum
Anus, margin
Axillary fold
Perianal skin
Skin of:
abdominal wall
anus
back
breast
buttock
chest wall
groin
perineum
Umbilicus
Excludes:	anal canal (230.5)
anus NOS (230.6)
skin of genital organs (233.30-233.39, 233.5-233.6)
232.6	Skin of upper limb, including shoulder
232.7	Skin of lower limb, including hip
232.8	Other specified sites of skin
232.9	Skin, site unspecified
233	Carcinoma in situ of breast and genitourinary system
233.0	Breast
Excludes:	Paget's disease (174.0-174.9)
skin of breast (232.5)
233.1	Cervix uteri
Adenocarcinoma in situ of cervix
Cervical intraepithelial glandular neoplasia
Cervical intraepithelial neoplasia III [CIN III]
Severe dysplasia of cervix
Excludes:	cervical intraepithelial neoplasia II [CIN II] (622.12)
cytologic evidence of malignancy without histologic confirmation (795.06)
high grade squamous intraepithelial lesion (HGSIL) (795.04)
moderate dysplasia of cervix (622.12)
233.2	Other and unspecified parts of uterus
233.3	Other and unspecified female genital organs
233.30	Unspecified female genital organ
233.31	Vagina
Severe dysplasia of vagina
Vaginal intraepithelial neoplasia [VAIN III]
233.32	Vulva
Severe dysplasia of vulva
Vulvar intraepithelial neoplasia [VIN III]
233.39	Other female genital organ
233.4	Prostate
233.5	Penis
233.6	Other and unspecified male genital organs
233.7	Bladder
233.9	Other and unspecified urinary organs
234	Carcinoma in situ of other and unspecified sites
234.0	Eye
Excludes:	cartilage of eyelid (234.8)
eyelid (skin) (232.1)
optic nerve (234.8)
orbital bone (234.8)
234.8	Other specified sites
Endocrine gland [any]
234.9	Site unspecified
Carcinoma in situ NOS

NEOPLASMS OF UNCERTAIN BEHAVIOR (235-238)

Note:	Categories 235-238 classify by site certain histo-morphologically well-defined
 neoplasms, the subsequent behavior of which cannot be predicted from the present appearance.
235	Neoplasm of uncertain behavior of digestive and respiratory systems
Excludes:	stromal tumors of uncertain behavior of digestive system (238.1)
235.0	Major salivary glands
Gland:
parotid
sublingual
submandibular
Excludes:	minor salivary glands (235.1)
235.1	Lip, oral cavity, and pharynx
Gingiva
Hypopharynx
Minor salivary glands
Mouth
Nasopharynx
Oropharynx
Tongue
Excludes:	aryepiglottic fold or interarytenoid fold, laryngeal aspect (235.6)
epiglottis:
NOS (235.6)
suprahyoid portion (235.6)
skin of lip (238.2)
235.2	Stomach, intestines, and rectum
235.3	Liver and biliary passages
Ampulla of Vater
Bile ducts [any]
Gallbladder
Liver
235.4	Retroperitoneum and peritoneum
235.5	Other and unspecified digestive organs
Anal:
canal
sphincter
Anus NOS
Esophagus
Pancreas
Spleen
Excludes:	anus:
margin (238.2)
skin (238.2)
perianal skin (238.2)
235.6	Larynx
Excludes:	aryepiglottic fold or interarytenoid fold:
NOS (235.1)
hypopharyngeal aspect (235.1)
marginal zone (235.1)
235.7	Trachea, bronchus, and lung
235.8	Pleura, thymus, and mediastinum
235.9	Other and unspecified respiratory organs
Accessory sinuses
Middle ear
Nasal cavities
Respiratory organ NOS
Excludes:	ear (external) (skin) (238.2)
nose (238.8)
skin (238.2)
236	Neoplasm of uncertain behavior of genitourinary organs
236.0	Uterus
236.1	Placenta
Chorioadenoma (destruens)
Invasive mole
Malignant hydatid(iform) mole
236.2	Ovary
Use additional code to identify any functional activity
236.3	Other and unspecified female genital organs
236.4	Testis
Use additional code to identify any functional activity
236.5	Prostate
236.6	Other and unspecified male genital organs
236.7	Bladder
236.9	Other and unspecified urinary organs
236.90	Urinary organ, unspecified
236.91	Kidney and ureter
236.99	Other
237	Neoplasm of uncertain behavior of endocrine glands and nervous system
237.0	Pituitary gland and craniopharyngeal duct
Use additional code to identify any functional activity
237.1	Pineal gland
237.2	Adrenal gland
Suprarenal gland
Use additional code to identify any functional activity
237.3	Paraganglia
Aortic body
Carotid body
Coccygeal body
Glomus jugulare
237.4	Other and unspecified endocrine glands
Parathyroid gland
Thyroid gland
237.5	Brain and spinal cord
237.6	Meninges
Meninges:
NOS
cerebral
spinal
237.7	Neurofibromatosis
von Recklinghausen's disease
237.70	Neurofibromatosis, unspecified
237.71	Neurofibromatosis, type 1 [von Recklinghausen's disease]
237.72	Neurofibromatosis, type 2 [acoustic neurofibromatosis]
237.9	Other and unspecified parts of nervous system
Cranial nerves
Excludes:	peripheral, sympathetic, and parasympathetic nerves and ganglia (238.1)
238	Neoplasm of uncertain behavior of other and unspecified sites and tissues
238.0	Bone and articular cartilage
Excludes:	cartilage:
ear (238.1)
eyelid (238.1)
larynx (235.6)
nose (235.9)
synovia (238.1)
238.1	Connective and other soft tissue
Peripheral, sympathetic, and parasympathetic nerves and ganglia
Stromal tumors of digestive system
Excludes:	cartilage (of):
articular (238.0)
larynx (235.6)
nose (235.9)
connective tissue of breast (238.3)
238.2	Skin
Excludes:	anus NOS (235.5)
skin of genital organs (236.3, 236.6)
vermilion border of lip (235.1)
238.3	Breast
Excludes:	skin of breast (238.2)
238.4	Polycythemia vera
238.5	Histiocytic and mast cells
Mast cell tumor NOS
Mastocytoma NOS
238.6	Plasma cells
Plasmacytoma NOS
Solitary myeloma
238.7	Other lymphatic and hematopoietic tissues
Excludes:	acute myelogenous leukemia (205.0)
chronic myelomonocytic leukemia (205.1)
myelofibrosis (289.83)
myelosclerosis NOS (289.89)
myelosis:
NOS (205.9)
megakaryocytic (207.2)
238.71	Essential thrombocythemia
Essential hemorrhagic thrombocythemia
Essential thrombocytosis
Idiopathic (hemorrhagic) thrombocythemia
Primary thrombocytosis
238.72	Low grade myelodysplastic syndrome lesions
Refractory anemia (RA)
Refractory anemia with ringed sideroblasts (RARS)
Refractory cytopenia with multilineage dysplasia (RCMD)
Refractory cytopenia with multilineage dysplasia and ringed sideroblasts (RCMD-RS)
238.73	High grade myelodysplastic syndrome lesions
Refractory anemia with excess blasts-1 (RAEB-1)
Refractory anemia with excess blasts-2 (RAEB-2)
238.74	Myelodysplastic syndrome with 5q deletion
5q minus syndrome NOS
Excludes:	constitutional 5q deletion (758.39)
high grade myelodysplastic syndrome with 5q deletion (238.73)
238.75	Myelodysplastic syndrome, unspecified
238.76	Myelofibrosis with myeloid metaplasia
Agnogenic myeloid metaplasia
Idiopathic myelofibrosis (chronic)
Myelosclerosis with myeloid metaplasia
Primary myelofibrosis
Excludes:	myelofibrosis NOS (289.83)
myelophthisic anemia (284.2)
myelophthisis (284.2)
secondary myelofibrosis (289.83)
238.79	Other lymphatic and hematopoietic tissues
Lymphoproliferative disease (chronic) NOS
Megakaryocytic myelosclerosis
Myeloproliferative disease (chronic) NOS
Panmyelosis (acute)
238.8	Other specified sites
Eye
Heart
Excludes:	eyelid (skin) (238.2)
cartilage (238.1)
238.9	Site unspecified

NEOPLASMS OF UNSPECIFIED NATURE (239)

239	Neoplasms of unspecified nature
Note:	Category 239 classifies by site neoplasms of unspecified morphology and behavior.
 The term "mass," unless otherwise stated, is not to be regarded as a neoplastic growth.
Includes:	"growth" NOS
neoplasm NOS
new growth NOS
tumor NOS
239.0	Digestive system
Excludes:	anus:
margin (239.2)
skin (239.2)
perianal skin (239.2)
239.1	Respiratory system
239.2	Bone, soft tissue, and skin
Excludes:	anal canal (239.0)
anus NOS (239.0)
bone marrow (202.9)
cartilage:
larynx (239.1)
nose (239.1)
connective tissue of breast (239.3)
skin of genital organs (239.5)
vermilion border of lip (239.0)
239.3	Breast
Excludes:	skin of breast (239.2)
239.4	Bladder
239.5	Other genitourinary organs
239.6	Brain
Excludes:	cerebral meninges (239.7)
cranial nerves (239.7)
239.7	Endocrine glands and other parts of nervous system
Excludes:	peripheral, sympathetic, and parasympathetic nerves and ganglia (239.2)
239.8	Other specified sites
Excludes:	eyelid (skin) (239.2)
cartilage (239.2)
great vessels (239.2)
optic nerve (239.7)
239.9	Site unspecified